Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity.

Hanna, Joachim; Beke, Flavio; O'Brien, Louise M; Kapeni, Chrysa; Chen, Hung-Chang; Carbonaro, Valentina; Kim, Alexander B; Kishore, Kamal; Adolph, Timon E; Skjoedt, Mikkel-Ole; Skjoedt, Karsten; de la Roche, Marc; de la Roche, Maike

Hanna, Joachim; Beke, Flavio; O'Brien, Louise M; Kapeni, Chrysa; Chen, Hung-Chang; Carbonaro, Valentina; Kim, Alexander B; Kishore, Kamal; Adolph, Timon E; Skjoedt, Mikkel-Ole; Skjoedt, Karsten; de la Roche, Marc; de la Roche, Maike.

Afiliación

Hanna J; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Beke F; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
O'Brien LM; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Kapeni C; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Chen HC; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Carbonaro V; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Kim AB; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Kishore K; Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
Adolph TE; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
Skjoedt MO; Rigshospitalet - University Hospital Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Skjoedt K; Institute of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
de la Roche M; University of Southern Denmark, J.B.Winslows Vej, 5000, Odense C, Denmark.
de la Roche M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.

Nat Commun ; 13(1): 4075, 2022 07 14.

Article en En | MEDLINE | ID: mdl-35835905

Asunto(s)

Colitis Ulcerosa; Células Th17; Adulto; Animales; Colitis Ulcerosa/tratamiento farmacológico; Colitis Ulcerosa/genética; Proteínas Hedgehog/genética; Proteínas Hedgehog/metabolismo; Humanos; Ratones; Transducción de Señal; Virulencia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Células Th17 Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido

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