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GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level.
Lin, Zhi-Rong; Li, Zhen-Zhen; Cao, Yan-Jun; Yu, Wen-Jing; Ye, Jian-Tao; Liu, Pei-Qing.
Afiliación
  • Lin ZR; School of Pharmaceutical Sciences, Sun Yat-Sen University, National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China.
  • Li ZZ; School of Pharmaceutical Sciences, Sun Yat-Sen University, National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China.
  • Cao YJ; School of Pharmaceutical Sciences, Sun Yat-Sen University, National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China.
  • Yu WJ; School of Pharmaceutical Sciences, Sun Yat-Sen University, National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China.
  • Ye JT; School of Pharmaceutical Sciences, Sun Yat-Sen University, National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China. yejt@mail.sysu.edu.cn.
  • Liu PQ; School of Pharmaceutical Sciences, Sun Yat-Sen University, National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China. liupq@mail.sysu.edu.cn.
Naunyn Schmiedebergs Arch Pharmacol ; 395(11): 1373-1385, 2022 11.
Article en En | MEDLINE | ID: mdl-35904584
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glutamato Deshidrogenasa / Ácidos Cetoglutáricos Límite: Animals Idioma: En Revista: Naunyn Schmiedebergs Arch Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glutamato Deshidrogenasa / Ácidos Cetoglutáricos Límite: Animals Idioma: En Revista: Naunyn Schmiedebergs Arch Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania