Artificial Nucleobase-Directed Programmable Synthesis and Assembly of Amphiphilic Nucleic Acids as an All-in-One Platform for Cation-Free siRNA Delivery.

Luo, Can; Xie, Yuqi; He, Minze; Xia, Yinghao; Li, Yazhou; He, Lei; Li, Jili; Wang, Linlin; Han, Xiaoyan; Zhang, Lili; Yuan, Xi; Wang, Zhiqiang; Liu, Yanlan; Tan, Weihong

Luo, Can; Xie, Yuqi; He, Minze; Xia, Yinghao; Li, Yazhou; He, Lei; Li, Jili; Wang, Linlin; Han, Xiaoyan; Zhang, Lili; Yuan, Xi; Wang, Zhiqiang; Liu, Yanlan; Tan, Weihong.

Afiliación

Luo C; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Xie Y; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
He M; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Xia Y; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Li Y; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
He L; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou 310022, Zhejiang, China.
Li J; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Wang L; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Han X; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Zhang L; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Yuan X; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Wang Z; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Liu Y; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.
Tan W; Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hu-nan University, Changsha 410082, Hunan, China.

ACS Appl Mater Interfaces ; 14(39): 44019-44028, 2022 Oct 05.

Article en En | MEDLINE | ID: mdl-36149091

Asunto(s)

Ácidos Nucleicos; Cationes; Endosomas; Silenciador del Gen; Ácidos Nucleicos/química; ARN Interferente Pequeño/química

Palabras clave

amphiphilic nucleic acid; artificial nucleobase; cancer theranostics; cation-free nucleic acid delivery; molecular recognition

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Nucleicos Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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