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The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin-1α release from human blood cells.
Wiggins, Kimberley A; Pyrillou, Katerina; Humphry, Melanie; Butterworth, Adam S; Clarke, Murray Ch.
Afiliación
  • Wiggins KA; Section of CardioRespiratory Medicine, Department of Medicine, University of Cambridge, The Heart & Lung Research Institute, Cambridge, UK.
  • Pyrillou K; Section of CardioRespiratory Medicine, Department of Medicine, University of Cambridge, The Heart & Lung Research Institute, Cambridge, UK.
  • Humphry M; Section of CardioRespiratory Medicine, Department of Medicine, University of Cambridge, The Heart & Lung Research Institute, Cambridge, UK.
  • Butterworth AS; Dept of Public Health and Primary Care, University of Cambridge, The Heart & Lung Research Institute, Cambridge, UK.
  • Clarke MC; Section of CardioRespiratory Medicine, Department of Medicine, University of Cambridge, The Heart & Lung Research Institute, Cambridge, UK.
Immunology ; 168(3): 459-472, 2023 03.
Article en En | MEDLINE | ID: mdl-36175368

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Interleucina-1alfa Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Immunology Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Interleucina-1alfa Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Immunology Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido