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A FFAR1 full agonist restores islet function in models of impaired glucose-stimulated insulin secretion and diabetic non-human primates.
Rady, Brian; Liu, Jianying; Huang, Hui; Bakaj, Ivona; Qi, Jenson; Lee, S P; Martin, Tonya; Norquay, Lisa; Player, Mark; Pocai, Alessandro.
Afiliación
  • Rady B; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Liu J; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Huang H; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Bakaj I; Discovery Chemistry, Janssen R&D, Spring House, PA, United States.
  • Qi J; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Lee SP; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Martin T; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Norquay L; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
  • Player M; Medical Affairs, Janssen R&D, Spring House, PA, United States.
  • Pocai A; Cardiovascular and Metabolism Discovery, Janssen Research and Development, Spring House, PA, United States.
Front Endocrinol (Lausanne) ; 13: 1061688, 2022.
Article en En | MEDLINE | ID: mdl-36482991
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Acoplados a Proteínas G / Diabetes Mellitus Tipo 2 / Secreción de Insulina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Acoplados a Proteínas G / Diabetes Mellitus Tipo 2 / Secreción de Insulina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza