Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages.

Shi, Liangliang; Jiang, Zhengying; Li, Jiaqi; Lin, Huan; Xu, Bin; Liao, Xincheng; Fu, Zhonghua; Ao, Haiyong; Guo, Guanghua; Liu, Mingzhuo

Shi, Liangliang; Jiang, Zhengying; Li, Jiaqi; Lin, Huan; Xu, Bin; Liao, Xincheng; Fu, Zhonghua; Ao, Haiyong; Guo, Guanghua; Liu, Mingzhuo.

Afiliación

Shi L; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Jiang Z; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Li J; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Lin H; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Xu B; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Liao X; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Fu Z; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Ao H; Jiangxi Key Laboratory of Nanobiomaterials, Institute of Advanced Materials, East China Jiaotong University, Nanchang 330013, China.
Guo G; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Liu M; Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China.

Cells ; 11(24)2022 12 16.

Article en En | MEDLINE | ID: mdl-36552856

Asunto(s)

Quemaduras; Metformina; Ratas; Animales; Ratones; Metformina/farmacología; Metformina/uso terapéutico; Fibroblastos/metabolismo; Lipopolisacáridos/farmacología; Cicatrización de Heridas; Colágeno/metabolismo; Macrófagos/metabolismo; Colágeno Tipo I/metabolismo; Quemaduras/tratamiento farmacológico; ARN Mensajero/metabolismo

Palabras clave

AMPK; NF-κB; burn; co-culture; collagen I; mTOR; metformin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quemaduras / Metformina Límite: Animals Idioma: En Revista: Cells Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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