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Targeted degradation via direct 26S proteasome recruitment.
Bashore, Charlene; Prakash, Sumit; Johnson, Matthew C; Conrad, Ryan J; Kekessie, Ivy A; Scales, Suzie J; Ishisoko, Noriko; Kleinheinz, Tracy; Liu, Peter S; Popovych, Nataliya; Wecksler, Aaron T; Zhou, Lijuan; Tam, Christine; Zilberleyb, Inna; Srinivasan, Rajini; Blake, Robert A; Song, Aimin; Staben, Steven T; Zhang, Yingnan; Arnott, David; Fairbrother, Wayne J; Foster, Scott A; Wertz, Ingrid E; Ciferri, Claudio; Dueber, Erin C.
Afiliación
  • Bashore C; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Prakash S; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA.
  • Johnson MC; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA.
  • Conrad RJ; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA.
  • Kekessie IA; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Scales SJ; Department of Immunology, Genentech Inc., South San Francisco, CA, USA.
  • Ishisoko N; Department of Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA, USA.
  • Kleinheinz T; Department of Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA, USA.
  • Liu PS; Department of Microchemistry, Proteomics, and Lipidomics, Genentech Inc., South San Francisco, CA, USA.
  • Popovych N; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Wecksler AT; Department of Protein Analytical Chemistry, Genentech Inc., South San Francisco, CA, USA.
  • Zhou L; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Tam C; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA, USA.
  • Zilberleyb I; Department of Biomolecular Resources, Genentech Inc., South San Francisco, CA, USA.
  • Srinivasan R; Department of Molecular Biology, Genentech Inc., South San Francisco, CA, USA.
  • Blake RA; Department of Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, CA, USA.
  • Song A; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Staben ST; Department of Discovery Chemistry, Genentech Inc., South San Francisco, CA, USA.
  • Zhang Y; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Arnott D; Department of Microchemistry, Proteomics, and Lipidomics, Genentech Inc., South San Francisco, CA, USA.
  • Fairbrother WJ; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
  • Foster SA; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA.
  • Wertz IE; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA. ingrid@lyterian.com.
  • Ciferri C; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA. ingrid@lyterian.com.
  • Dueber EC; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA. ciferri.claudio@gene.com.
Nat Chem Biol ; 19(1): 55-63, 2023 01.
Article en En | MEDLINE | ID: mdl-36577875
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos