Asperosaponin VI Protects Against Bone Loss Due to Hindlimb Unloading in Skeletally Growing Mice Through Regulating Microbial Dysbiosis Altering the 5-HT Pathway.

Niu, Y-B; Zhang, Y-H; Sun, Y; Song, X-Z; Li, Z-H; Xie, M; Mei, Q-B; Li, Y-H; Chen, Q

Niu, Y-B; Zhang, Y-H; Sun, Y; Song, X-Z; Li, Z-H; Xie, M; Mei, Q-B; Li, Y-H; Chen, Q.

Afiliación

Niu YB; Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China.
Zhang YH; State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China.
Sun Y; Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi, People's Republic of China.
Song XZ; Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China.
Li ZH; Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China.
Xie M; Department of Pharmacy, The First Naval Force Hospital of Southern Theatre Command, Zhanjiang, 524005, Guangdong, People's Republic of China.
Mei QB; Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China.
Li YH; Department of Pathology, The First Naval Force Hospital of Southern Theatre Command, Zhanjiang, 524005, Guangdong, People's Republic of China. yuhualee973@126.com.
Chen Q; State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, People's Republic of China. chenqiang0213@126.com.

Calcif Tissue Int ; 112(3): 389-402, 2023 03.

Article en En | MEDLINE | ID: mdl-36595050

Asunto(s)

Suspensión Trasera; Osteoporosis; Ratones; Femenino; Animales; Suspensión Trasera/fisiología; Serotonina; Disbiosis; Ratones Endogámicos C57BL; Osteoporosis/etiología

Palabras clave

16sRNA; 5-hydroxytryptophan; Asperosaponin VI; Bone loss; Metabolomics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Suspensión Trasera Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Calcif Tissue Int Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

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