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Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone).
Ivasechko, Iryna; Lozynskyi, Andrii; Senkiv, Julia; Roszczenko, Piotr; Kozak, Yuliia; Finiuk, Nataliya; Klyuchivska, Olga; Kashchak, Nataliya; Manko, Nazar; Maslyak, Zvenyslava; Lesyk, Danylo; Karkhut, Andriy; Polovkovych, Svyatoslav; Czarnomysy, Robert; Szewczyk, Olga; Kozytskiy, Andriy; Karpenko, Olexandr; Khyluk, Dmytro; Gzella, Andrzej; Bielawski, Krzysztof; Bielawska, Anna; Dzubak, Petr; Gurska, Sona; Hajduch, Marian; Stoika, Rostyslav; Lesyk, Roman.
Afiliación
  • Ivasechko I; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Lozynskyi A; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv, 79010, Ukraine.
  • Senkiv J; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Roszczenko P; Department of Biotechnology, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilinskiego 1, 15-089, Bialystok, Poland.
  • Kozak Y; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Finiuk N; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Klyuchivska O; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Kashchak N; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Manko N; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine.
  • Maslyak Z; Institute of Blood Pathology and Transfusion Medicine of National Academy of Medical Sciences of Ukraine, General Chuprynky 45, Lviv, 79044, Ukraine.
  • Lesyk D; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv, 79010, Ukraine.
  • Karkhut A; Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera 12, Lviv, 79013, Ukraine.
  • Polovkovych S; Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera 12, Lviv, 79013, Ukraine.
  • Czarnomysy R; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilinskiego 1, 15-089, Bialystok, Poland.
  • Szewczyk O; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilinskiego 1, 15-089, Bialystok, Poland.
  • Kozytskiy A; Enamine Ltd, Chervonotkatska Street 78, Kyiv, 02094, Ukraine; L.V. Pysarzhevsky Institute of Physical Chemistry, National Academy of Sciences of Ukraine, Nauky Avenue 31, Kyiv, 03028, Ukraine.
  • Karpenko O; Enamine Ltd, Chervonotkatska Street 78, Kyiv, 02094, Ukraine.
  • Khyluk D; Department of Organic Chemistry, Faculty of Pharmacy with Medical Analytics Division, Medical University of Lublin, 4A Chodzki, Lublin, 20-093, Poland.
  • Gzella A; Department of Organic Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780, Poznan, Poland.
  • Bielawski K; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilinskiego 1, 15-089, Bialystok, Poland.
  • Bielawska A; Department of Biotechnology, Faculty of Pharmacy, Medical University of Bialystok, Jana Kilinskiego 1, 15-089, Bialystok, Poland.
  • Dzubak P; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Hnevotinska 5, 77900, Olomouc, Czech Republic.
  • Gurska S; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Hnevotinska 5, 77900, Olomouc, Czech Republic.
  • Hajduch M; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Hnevotinska 5, 77900, Olomouc, Czech Republic.
  • Stoika R; Institute of Cell Biology of National Academy of Sciences of Ukraine, Drahomanov14/16, Lviv, 79005, Ukraine. Electronic address: stoika.rostyslav@gmail.com.
  • Lesyk R; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, Lviv, 79010, Ukraine; Department of Biotechnology and Cell Biology, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225,
Eur J Med Chem ; 252: 115304, 2023 Apr 05.
Article en En | MEDLINE | ID: mdl-37001390
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Naftoquinonas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Naftoquinonas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Francia