Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP-<i>Î³</i>-cyclodextrin.

Ding, Yili; Yu, Bo; Zhou, Shuzhen; Ding, Charles; Zhang, Zhiyuan; Xu, Shufeng; Xu, Zhe

Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP-Î³-cyclodextrin.

Ding, Yili; Yu, Bo; Zhou, Shuzhen; Ding, Charles; Zhang, Zhiyuan; Xu, Shufeng; Xu, Zhe.

Afiliación

Ding Y; College of Science and Technology, Wenzhou-Kean University, Wenzhou, Zhejiang, China.
Yu B; Life Science Department, Foshan University, Foshan, Guangdong, China.
Zhou S; Eastern Along Pharmaceutical Co., Ltd., Foshan, Guangdong, China.
Ding C; Keck School of Medicine of USC, Los Angeles, CA, United States.
Zhang Z; Life Science Department, Foshan University, Foshan, Guangdong, China.
Xu S; Life Science Department, Foshan University, Foshan, Guangdong, China.
Xu Z; College of Science and Technology, Wenzhou-Kean University, Wenzhou, Zhejiang, China.

Front Pharmacol ; 14: 1138686, 2023.

Article en En | MEDLINE | ID: mdl-37033648

Palabras clave

cyclodextrin; icariin; in vitro and in vivo PK study; inclusion complex; water solubility

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google