Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition.

Bishop, Timothy R; Subramanian, Chitra; Bilotta, Eric M; Garnar-Wortzel, Leopold; Ramos, Anissa R; Zhang, Yuxiang; Asiaban, Joshua N; Ott, Christopher J; Rock, Charles O; Erb, Michael A

Bishop, Timothy R; Subramanian, Chitra; Bilotta, Eric M; Garnar-Wortzel, Leopold; Ramos, Anissa R; Zhang, Yuxiang; Asiaban, Joshua N; Ott, Christopher J; Rock, Charles O; Erb, Michael A.

Afiliación

Bishop TR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Subramanian C; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.
Bilotta EM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Garnar-Wortzel L; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Ramos AR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Zhang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Asiaban JN; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Ott CJ; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA.
Rock CO; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Erb MA; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.

Nat Chem Biol ; 19(10): 1215-1222, 2023 10.

Article en En | MEDLINE | ID: mdl-37127754

Asunto(s)

Histona Acetiltransferasas; Neoplasias; Humanos; Histona Acetiltransferasas/metabolismo; Factores de Transcripción p300-CBP/metabolismo; Acetilcoenzima A/metabolismo; Unión Proteica

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histona Acetiltransferasas / Neoplasias Límite: Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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