Posttraumatic osteoarthritis: from basic science to clinical implications.
OTA Int
; 6(2 Suppl): e232, 2023 May.
Article
en En
| MEDLINE
| ID: mdl-37168031
ABSTRACT
Posttraumatic osteoarthritis (PTOA) is a subset of osteoarthritis that occurs after joint injury and is associated with degradation of articular cartilage and subchondral bone. As compared with primary osteoarthritis, PTOA occurs in a time window initiated by a traumatic event resulting in damage to layers of joint structure and alterations in joint shape. As techniques in open reduction and internal fixation continue to mature, our success in preventing posttraumatic osteoarthritis has not kept pace. Advances in research in the subchondral bone, inflammatory response, and joint mechanics continue to open our understanding of this posttraumatic process. In addition, there are possibilities emerging as biological agents to therapeutically alter the progression of PTOA.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
OTA Int
Año:
2023
Tipo del documento:
Article