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DNA templated Click Chemistry via 5-vinyl-2'-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells.
Li, Yizhu; Ling, Yurong; Loehr, Morten O; Chaabane, Sabrina; Cheng, Oh Wan; Zhao, Kaifeng; Wu, Chao; Büscher, Moritz; Weber, Jana; Stomakhine, Daria; Munker, Marina; Pientka, Ronja; Christ, Sarah B; Dobbelstein, Matthias; Luedtke, Nathan W.
Afiliación
  • Li Y; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany. Electronic address: yizhu.li@tum.de.
  • Ling Y; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Loehr MO; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada.
  • Chaabane S; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Cheng OW; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Zhao K; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada.
  • Wu C; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Büscher M; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Weber J; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Stomakhine D; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada.
  • Munker M; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Pientka R; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Christ SB; 2(nd) Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22 81675 Munich, Germany.
  • Dobbelstein M; Department of Molecular Oncology, Göttingen Center of Molecular Biosciences (GZMB), University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Luedtke NW; Department of Chemistry, McGill University, 845 Sherbrooke St W, Montreal, Quebec H3A 0G4, Canada; Department of Pharmacology and Therapeutics, McGill University, Montréal H3G 1Y6, Canada.
Life Sci ; 330: 122000, 2023 Oct 01.
Article en En | MEDLINE | ID: mdl-37541577
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Química Clic / Neoplasias Límite: Humans Idioma: En Revista: Life Sci Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Química Clic / Neoplasias Límite: Humans Idioma: En Revista: Life Sci Año: 2023 Tipo del documento: Article