Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1&#945; pathway.

Zeng, Jia; Wang, Ying; Zhu, Manhui; Wu, Min; Zhou, Yamei; Wang, Qiaoyun; Xu, Yiqian; Lin, Fei; Wang, Jiaqi; Li, Yuxuan; Liang, Shuang; Wang, Ziyu; Xie, Laiqing; Liu, Xiaojuan

Neutrophil extracellular traps boost laser-induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF-1α pathway.

Zeng, Jia; Wang, Ying; Zhu, Manhui; Wu, Min; Zhou, Yamei; Wang, Qiaoyun; Xu, Yiqian; Lin, Fei; Wang, Jiaqi; Li, Yuxuan; Liang, Shuang; Wang, Ziyu; Xie, Laiqing; Liu, Xiaojuan.

Afiliación

Zeng J; Department of Pathogen Biology, Medical College, Nantong University, China.
Wang Y; Department of Ophthalmology, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, China.
Zhu M; Department of Pathology, Lixiang Eye Hospital of Soochow University, Suzhou, China.
Wu M; Department of Pathogen Biology, Medical College, Nantong University, China.
Zhou Y; Department of Pathogen Biology, Medical College, Nantong University, China.
Wang Q; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Xu Y; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Lin F; Medical College, Nantong University, China.
Wang J; Medical College, Nantong University, China.
Li Y; Medical College, Nantong University, China.
Liang S; Medical College, Nantong University, China.
Wang Z; Medical College, Nantong University, China.
Xie L; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Liu X; Department of Pathogen Biology, Medical College, Nantong University, China.

FEBS J ; 290(22): 5395-5410, 2023 11.

Article en En | MEDLINE | ID: mdl-37552110

Asunto(s)

Neovascularización Coroidal; Trampas Extracelulares; Ratones; Humanos; Animales; Células Endoteliales/metabolismo; Receptor Toll-Like 4/genética; Metaloproteinasa 9 de la Matriz/genética; Factor A de Crecimiento Endotelial Vascular/metabolismo; Neovascularización Coroidal/genética; Modelos Animales de Enfermedad; Rayos Láser; Subunidad alfa del Factor 1 Inducible por Hipoxia/genética

Palabras clave

Toll-like receptor 4; choroidal endothelial cells; choroidal neovascularization; hypoxia inducible factor-1α; neutrophil extracellular trap

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neovascularización Coroidal / Trampas Extracelulares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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