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Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects.
Zhao, Ziqi; Zhang, Jungan; Ren, Yixin; Dong, Luyao; Wu, Han; Hong, Wei; Huang, Huoqiang; Yang, Xinyi; Pang, Zongran; Wang, Hao.
Afiliación
  • Zhao Z; School of Pharmacy, Minzu University of China, Beijing 100081, PR China; Key Laboratory of Ethnomedicine (MinZu University of China), Ministry of Education, Beijing 100081, PR China.
  • Zhang J; School of Pharmacy, Minzu University of China, Beijing 100081, PR China; Key Laboratory of Ethnomedicine (MinZu University of China), Ministry of Education, Beijing 100081, PR China.
  • Ren Y; Institute of National Security, Minzu University of China, Beijing 100081, PR China.
  • Dong L; Beijing Key Laboratory of Antimicrobial Agents/Laboratory of Pharmacology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China.
  • Wu H; School of Pharmacy, Minzu University of China, Beijing 100081, PR China; Key Laboratory of Ethnomedicine (MinZu University of China), Ministry of Education, Beijing 100081, PR China.
  • Hong W; Jingjinji National Center of Technology Innovation, Beijing 100094, PR China.
  • Huang H; School of Pharmacy, Minzu University of China, Beijing 100081, PR China; Key Laboratory of Ethnomedicine (MinZu University of China), Ministry of Education, Beijing 100081, PR China.
  • Yang X; Beijing Key Laboratory of Antimicrobial Agents/Laboratory of Pharmacology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China. Electronic address: xinyiyang@imb.cams.cn.
  • Pang Z; School of Pharmacy, Minzu University of China, Beijing 100081, PR China; Key Laboratory of Ethnomedicine (MinZu University of China), Ministry of Education, Beijing 100081, PR China. Electronic address: pangzongran@muc.edu.cn.
  • Wang H; School of Pharmacy, Minzu University of China, Beijing 100081, PR China; Key Laboratory of Ethnomedicine (MinZu University of China), Ministry of Education, Beijing 100081, PR China; Institute of National Security, Minzu University of China, Beijing 100081, PR China. Electronic address: hao.wang@muc
Bioorg Med Chem ; 92: 117436, 2023 09 07.
Article en En | MEDLINE | ID: mdl-37556911
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Cuello Uterino / Inhibidores Enzimáticos Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Cuello Uterino / Inhibidores Enzimáticos Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido