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Renal Cell Carcinoma and Hepatocellular Carcinoma in a Patient with Wilson's Disease.
Kitahata, Shogo; Michitaka, Kojiro; Kinebuchi, Miyuki; Matsuura, Akihiro; Hiraoka, Atsushi; Ohama, Hideko; Yanagihara, Emi; Saneto, Hironobu; Izumoto, Hirofumi; Kawamura, Tomoe; Kuroda, Taira; Tada, Fujimasa; Miyata, Hideki; Ninomiya, Tomoyuki; Hiasa, Yoichi.
Afiliación
  • Kitahata S; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Michitaka K; Department of Internal Medicine, Saiseikai Imabari Dai2 Hospital, Japan.
  • Kinebuchi M; First Department of Pathology, Sapporo Medical University, Japan.
  • Matsuura A; Research Integrity Office, Fujita Health University, Japan.
  • Hiraoka A; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Ohama H; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Yanagihara E; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Saneto H; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Izumoto H; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Kawamura T; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Kuroda T; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Tada F; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Miyata H; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Ninomiya T; Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
  • Hiasa Y; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Japan.
Intern Med ; 63(7): 963-968, 2024 Apr 01.
Article en En | MEDLINE | ID: mdl-37612087
No reports of renal cancer in patients with Wilson's disease (WD) exist. We herein report a 37-year-old Japanese man diagnosed with WD who had been treated with d-penicillamine 9 years prior. Hepatocellular carcinoma had been diagnosed at 36 years old and treated with radiofrequency ablation therapy. One year later, renal cancer and recurrent hepatocellular carcinoma had developed. The hepatocellular carcinoma was treated after renal cancer surgical resection of a clear-cell-type renal cell carcinoma, with iron, rather than copper, deposited on the renal cancer cells. This patient harbored a novel mutation, p. Leu1395Terfs in ATP7B.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Carcinoma Hepatocelular / Degeneración Hepatolenticular / Neoplasias Renales / Neoplasias Hepáticas Límite: Adult / Humans / Male Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Carcinoma Hepatocelular / Degeneración Hepatolenticular / Neoplasias Renales / Neoplasias Hepáticas Límite: Adult / Humans / Male Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón