Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM): The next frontier of drug discovery and disease understanding.

Barroso, Margarida; Monaghan, Michael G; Niesner, Raluca; Dmitriev, Ruslan I

Barroso, Margarida; Monaghan, Michael G; Niesner, Raluca; Dmitriev, Ruslan I.

Afiliación

Barroso M; Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.
Monaghan MG; Department of Mechanical, Manufacturing and Biomedical Engineering, Trinity College Dublin, Dublin 02, Ireland.
Niesner R; Dynamic and Functional In Vivo Imaging, Freie Universität Berlin and Biophysical Analytics, German Rheumatism Research Center, Berlin, Germany.
Dmitriev RI; Tissue Engineering and Biomaterials Group, Department of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, C. Heymanslaan 10, 9000 Ghent, Belgium; Ghent Light Microscopy Core, Ghent University, 9000 Ghent, Belgium. Electronic address: ruslan.dmitriev@ugent.be.

Adv Drug Deliv Rev ; 201: 115081, 2023 10.

Article en En | MEDLINE | ID: mdl-37647987

Asunto(s)

Microscopía; Organoides; Humanos; Descubrimiento de Drogas

Palabras clave

FLIM; Hypoxia; Metabolism; Microenvironment; Mitochondria; Organoids; PLIM

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Organoides / Microscopía Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Adv Drug Deliv Rev Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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