Easy and Versatile Technique for the Preparation of Stable and Active Lipase-Based CLEA-like Copolymers by Using Two Homofunctional Cross-Linking Agents: Application to the Preparation of Enantiopure Ibuprofen.

Khiari, Oussama; Bouzemi, Nassima; Sánchez-Montero, José María; Alcántara, Andrés R

Khiari, Oussama; Bouzemi, Nassima; Sánchez-Montero, José María; Alcántara, Andrés R.

Afiliación

Khiari O; Eco Compatible Asymmetric Catalysis Laboratory (LCAE), Department of Chemistry, Badji Mokhtar University, Annaba 23000, Algeria.
Bouzemi N; Department of Chemistry in Pharmaceutical Sciences, Pharmacy Faculty, Complutense University of Madrid (UCM), Ciudad Universitaria, Plaza de Ramon y Cajal, s/n., 28040 Madrid, Spain.
Sánchez-Montero JM; Eco Compatible Asymmetric Catalysis Laboratory (LCAE), Department of Chemistry, Badji Mokhtar University, Annaba 23000, Algeria.
Alcántara AR; Department of Chemistry in Pharmaceutical Sciences, Pharmacy Faculty, Complutense University of Madrid (UCM), Ciudad Universitaria, Plaza de Ramon y Cajal, s/n., 28040 Madrid, Spain.

Int J Mol Sci ; 24(17)2023 Sep 04.

Article en En | MEDLINE | ID: mdl-37686470

Asunto(s)

Ibuprofeno; Lipasa; Hidrólisis; Aminas; Catálisis; Polímeros

Palabras clave

CLEA-like copolymers; amine activation; cross-linkers; enzymatic hydrolysis; ibuprofen resolution; one-pot immobilization; pH jump

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ibuprofeno / Lipasa Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Argelia Pais de publicación: Suiza

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