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Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Chi, Gamma; Dietz, Larissa; Tang, Haiping; Snee, Matthew; Scacioc, Andreea; Wang, Dong; Mckinley, Gavin; Mukhopadhyay, Shubhashish M M; Pike, Ashley C W; Chalk, Rod; Burgess-Brown, Nicola A; Timmermans, Jean-Pierre; van Putte, Wouter; Robinson, Carol V; Dürr, Katharina L.
Afiliación
  • Chi G; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Dietz L; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Nuffield Department of Medicine Research Building, Oxford OX3 7FZ, UK.
  • Tang H; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Snee M; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK.
  • Scacioc A; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK.
  • Wang D; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Mckinley G; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Mukhopadhyay SMM; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Nuffield Department of Medicine Research Building, Oxford OX3 7FZ, UK.
  • Pike ACW; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Chalk R; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Nuffield Department of Medicine Research Building, Oxford OX3 7FZ, UK.
  • Burgess-Brown NA; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Timmermans JP; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Nuffield Department of Medicine Research Building, Oxford OX3 7FZ, UK.
  • van Putte W; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
  • Robinson CV; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Nuffield Department of Medicine Research Building, Oxford OX3 7FZ, UK.
  • Dürr KL; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.
Sci Adv ; 9(39): eadg8229, 2023 09 29.
Article en En | MEDLINE | ID: mdl-37774028

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Urea Límite: Humans Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Transporte de Membrana / Urea Límite: Humans Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido