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Functional, transcriptomic, and lipidomic studies of the choC gene encoding a phospholipid methyltransferase in Aspergillus fumigatus.
Pan, Jiao; Yang, Xinyu; Hu, Cuiting; Fu, Tongtong; Zhang, Xiuyan; Liu, Zijun; Wang, Yu; Zhang, Fengyu; He, Xiaoyuan; Yu, Jae-Hyuk.
Afiliación
  • Pan J; Institute for Cultural Heritage and History of Science and Technology, University of Science and Technology Beijing , Beijing, China.
  • Yang X; Department of Microbiology, College of Life Sciences, Nankai University , Tianjin, China.
  • Hu C; Department of Microbiology, College of Life Sciences, Nankai University , Tianjin, China.
  • Fu T; Department of Microbiology, College of Life Sciences, Nankai University , Tianjin, China.
  • Zhang X; College of Food Science and Technology, Huazhong Agricultural University , Wuhan, China.
  • Liu Z; Department of Microbiology, College of Life Sciences, Nankai University , Tianjin, China.
  • Wang Y; Institute for Cultural Heritage and History of Science and Technology, University of Science and Technology Beijing , Beijing, China.
  • Zhang F; Department of Microbiology, College of Life Sciences, Nankai University , Tianjin, China.
  • He X; Department of Hematology, Tianjin First Central Hospital , Tianjin, China.
  • Yu J-H; Department of Bacteriology, Food Research Institute, University of Wisconsin , Madison, Wisconsin, USA.
Microbiol Spectr ; 12(1): e0216823, 2024 Jan 11.
Article en En | MEDLINE | ID: mdl-38009944
IMPORTANCE: This study explored the phospholipid metabolic pathway in A. fumigatus and its relationship with fungal growth, metabolism, and pathogenicity. ChoC, based on its critical roles in many aspects of the fungus and relatively conserved characteristics in filamentous fungi with low similarity with mammalian ones, can be a novel target of new antifungal drugs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspergillus fumigatus / Lipidómica Límite: Animals Idioma: En Revista: Microbiol Spectr Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspergillus fumigatus / Lipidómica Límite: Animals Idioma: En Revista: Microbiol Spectr Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos