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Jelly snakes to reduce early postoperative vomiting in children after adenotonsillectomy: The randomized controlled snakes trial.
Sommerfield, David; Sommerfield, Aine; Evans, Daisy; Khan, R Nazim; Luke, Abigail; Vijayasekaran, Shyan; Bumbak, Paul; Herbert, Hayley; von Ungern-Sternberg, Britta S.
Afiliación
  • Sommerfield D; Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Perth, Australia; Perioperative Medicine Team, Perioperative Care Program, Telethon Kids Institute, Perth, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, Medical School, The University of Western Austr
  • Sommerfield A; Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Perth, Australia; Perioperative Medicine Team, Perioperative Care Program, Telethon Kids Institute, Perth, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, Medical School, The University of Western Austr
  • Evans D; Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Perth, Australia; Perioperative Medicine Team, Perioperative Care Program, Telethon Kids Institute, Perth, Australia; School of Physics, Mathematics and Computing, The University of Western Australia, Crawley, Australia.
  • Khan RN; Perioperative Medicine Team, Perioperative Care Program, Telethon Kids Institute, Perth, Australia; Department of Mathematics and Statistics, The University of Western Australia, Crawley, Australia.
  • Luke A; School of Biomedical Sciences, The University of Western Australia, Australia. Electronic address: abigail.luke@health.wa.gov.au.
  • Vijayasekaran S; Department of Otolaryngology/Head and Neck Surgery, Perth Children's Hospital, Nedlands, Australia.
  • Bumbak P; Department of Otolaryngology/Head and Neck Surgery, Perth Children's Hospital, Nedlands, Australia.
  • Herbert H; Department of Otolaryngology/Head and Neck Surgery, Perth Children's Hospital, Nedlands, Australia.
  • von Ungern-Sternberg BS; Department of Anaesthesia and Pain Medicine, Perth Children's Hospital, Perth, Australia; Perioperative Medicine Team, Perioperative Care Program, Telethon Kids Institute, Perth, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, Medical School, The University of Western Austr
Anaesth Crit Care Pain Med ; 43(1): 101334, 2024 Feb.
Article en En | MEDLINE | ID: mdl-38048987
BACKGROUND: Despite the use of dual antiemetic agents, postoperative nausea and vomiting (PONV) occurs in an unacceptably large number of patients post-tonsillectomy. There has been increased interest in alternative and non-pharmacological treatments for PONV e.g., chewing gum. We investigated if chewing a large confectionary jelly snake had prophylactic antiemetic effects postoperatively in young children. METHODS: Prospective, open-label randomised controlled trial of 240 patients, 2-16 years. Patients administered a confectionary jelly snake to chew postoperatively were compared with a control group. The primary outcome was the number of episodes of vomiting within 6 h of the operation on an intention-to-treat basis. SECONDARY OUTCOMES: incidence of nausea, vomiting at 6 and 24 h, rescue antiemetic use, acceptability, delayed discharge. RESULTS: 233 patients were randomised to receive the confectionary snake (snake group, 118) or standard care (control group, 115). The number of vomiting episodes in 6 h was similar between groups on an intention-to-treat basis, with 39 episodes across 22 (19%) patients in the control group and 31 across 19 (16%) patients in the snake group (p = 0.666). From post anaesthetic care unit until 24 h there was no difference in doses of antiemetics or delayed discharge due to PONV. A secondary as per protocol analysis did not change this result. CONCLUSIONS: Chewing of confectionery jelly snakes within one hour of waking following adenotonsillectomy with vapour-maintained anaesthesia and two prophylactic antiemetics did not further reduce the incidence of early vomiting. REGISTRATION: prospective registration at the Australia and New Zealand Clinical Trials Registry (ACTRN12618000637246).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonsilectomía / Antieméticos Límite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: Anaesth Crit Care Pain Med Año: 2024 Tipo del documento: Article Pais de publicación: Francia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonsilectomía / Antieméticos Límite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: Anaesth Crit Care Pain Med Año: 2024 Tipo del documento: Article Pais de publicación: Francia