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Whole cell hydride Meisenheimer complex biotransformation guided optimization of antimycobacterial benzothiazinones.
Joch, Melanie; Wojtas, K Philip; Torres-Gómez, Héctor; Li, Yan; Meyer, Florian; Straßburger, Maria; Kerndl, Valerie; Dahse, Hans-Martin; Hertweck, Christian; Hoffmann, Harald; Görls, Helmar; Walter, Kerstin; Hölscher, Christoph; Kloss, Florian.
Afiliación
  • Joch M; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Wojtas KP; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Torres-Gómez H; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Li Y; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Meyer F; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Straßburger M; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Kerndl V; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany.
  • Dahse HM; Infection Biology, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a, 07745, Jena, Germany.
  • Hertweck C; Biomolecular Chemistry, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a, 07745, Jena, Germany; Institute of Microbiology, Faculty of Biological Sciences, Friedrich Schiller University Jena, 07743, Jena, Germany.
  • Hoffmann H; Institute of Microbiology and Laboratory Medicine, IMLred GmbH, Robert-Koch-Allee 2, 82131, Gauting, Germany; SYNLAB Gauting, SYNLAB MVZ Dachau GmbH, Robert-Koch-Allee 2, 82131, Gauting, Germany.
  • Görls H; Institute of Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, Humboldtstrasse 8, 07743, Jena, Germany.
  • Walter K; Infection Immunology, Leibniz Lung Center, Research Center Borstel, Parkallee 1-40, 23845, Borstel, Germany; German Center for Infection Research (DZIF), Innenhofstrasse 7, 38124, Braunschweig, Germany.
  • Hölscher C; Infection Immunology, Leibniz Lung Center, Research Center Borstel, Parkallee 1-40, 23845, Borstel, Germany; German Center for Infection Research (DZIF), Innenhofstrasse 7, 38124, Braunschweig, Germany.
  • Kloss F; Transfer Group Anti-infectives, Leibniz Institute for Natural Products Research and Infection Biology, Leibniz-HKI, Beutenbergstr. 11a., 07745, Jena, Germany. Electronic address: Florian.Kloss@leibniz-hki.de.
Eur J Med Chem ; 264: 116023, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-38071794
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Francia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Francia