Heterodimers of Aromadendrane Sesquiterpenoid with Benzoquinone from the Chinese Liverwort Mylia nuda.
J Nat Prod
; 87(1): 132-140, 2024 01 26.
Article
en En
| MEDLINE
| ID: mdl-38157445
ABSTRACT
Mylnudones A-G (1-7), unprecedented 1,10-seco-aromadendrane-benzoquinone-type heterodimers, and a highly rearranged aromadendrane-type sesquiterpenoid (8), along with four known analogs (9-12), were isolated from the liverwort Mylia nuda. Compounds 1-6 and 7, bearing tricyclo[6.2.1.02,7] undecane and tricyclo[5.3.1.02,6] undecane backbones, likely formed via a Diels-Alder reaction and radical cyclization, respectively. Their structures were determined by spectroscopic analysis, computational calculation, and single-crystal X-ray diffraction analysis. Dimeric compounds displayed cytoprotective effects against glutamic acid-induced neurological deficits.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Hepatophyta
/
Sesquiterpenos de Guayano
/
Alcanos
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Nat Prod
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos