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Neurovascular Complications of Iatrogenic Fusarium solani Meningitis.
Strong, Nora; Meeks, Grant; Sheth, Sunil A; McCullough, Louise; Villalba, Julian A; Tan, Chunfeng; Barreto, Andrew; Wanger, Audrey; McDonald, Michelle; Kan, Peter; Shaltoni, Hashem; Campo Maldonado, Jose; Parada, Victoria; Hassan, Ameer E; Reagan-Steiner, Sarah; Chiller, Tom; Gold, Jeremy A W; Smith, Dallas J; Ostrosky-Zeichner, Luis.
Afiliación
  • Strong N; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Meeks G; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Sheth SA; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • McCullough L; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Villalba JA; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Tan C; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Barreto A; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Wanger A; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • McDonald M; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Kan P; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Shaltoni H; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Campo Maldonado J; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Parada V; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Hassan AE; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Reagan-Steiner S; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Chiller T; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Gold JAW; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Smith DJ; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
  • Ostrosky-Zeichner L; From McGovern Medical School, University of Texas Health Science Center at Houston, Houston (N.S., G.M., S.A.S., L.M., C.T., A.B., A.W., M.M., L.O.-Z.), the University of Texas Medical Branch, Galveston (P.K., H.S.), and the University of Texas Rio Grande Valley-Harlingen, Harlingen (J.C.M., V.P., A
N Engl J Med ; 390(6): 522-529, 2024 Feb 08.
Article en En | MEDLINE | ID: mdl-38324485
ABSTRACT
A multinational outbreak of nosocomial fusarium meningitis occurred among immunocompetent patients who had undergone surgery with epidural anesthesia in Mexico. The pathogen involved had a high predilection for the brain stem and vertebrobasilar arterial system and was associated with high mortality from vessel injury. Effective treatment options remain limited; in vitro susceptibility testing of the organism suggested that it is resistant to all currently approved antifungal medications in the United States. To highlight the severe complications associated with fusarium infection acquired in this manner, we report data, clinical courses, and outcomes from 13 patients in the outbreak who presented with symptoms after a median delay of 39 days.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Brotes de Enfermedades / Meningitis Fúngica / Fusariosis / Fusarium / Enfermedad Iatrogénica Tipo de estudio: Etiology_studies Límite: Humans País/Región como asunto: Mexico Idioma: En Revista: N Engl J Med Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Brotes de Enfermedades / Meningitis Fúngica / Fusariosis / Fusarium / Enfermedad Iatrogénica Tipo de estudio: Etiology_studies Límite: Humans País/Región como asunto: Mexico Idioma: En Revista: N Engl J Med Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos