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Celestial Insights: Unraveling the Role of miR-3682-3p in Hepatocellular Carcinoma.
Miao, Pei-Dong; Li, Ying; Jiang, Yu-Dong.
Afiliación
  • Miao PD; Dalian No.3 People's Hospital, Department of Interventional Radiology, Dalian, People's Republic of China.
  • Li Y; Dalian 7th People's Hospital, Dalian, Liaoning Province, China.
  • Jiang YD; Dalian No.3 People's Hospital, Department of Interventional Radiology, Dalian, People's Republic of China.
Clin Transl Gastroenterol ; 15(4): e00690, 2024 Apr 01.
Article en En | MEDLINE | ID: mdl-38334941
ABSTRACT
ABSTRACT Hepatocellular carcinoma (HCC) remains a formidable oncological challenge, calling for innovative therapeutic strategies to improve patient outcomes. MicroRNAs have emerged as key regulators in cancer, and miR-3682-3p shows potential as a diagnostic and prognostic biomarker in HCC. We conducted a comprehensive study to uncover its role in HCC biology, revealing dysregulation and clinical associations. Target gene analysis provided insights into potential molecular mechanisms. Moreover, we explored its impact on the tumor microenvironment, immune cell infiltration, and therapy responses. Our findings highlight miR-3682-3p as a promising candidate for further investigations and potential therapeutic strategies in HCC management.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / MicroARNs / Microambiente Tumoral / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Clin Transl Gastroenterol Año: 2024 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / MicroARNs / Microambiente Tumoral / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Clin Transl Gastroenterol Año: 2024 Tipo del documento: Article