Trends in thyroid function following radiofrequency ablation of benign, nonfunctioning thyroid nodules: A single institution review.
Am J Surg
; 237: 115793, 2024 Nov.
Article
en En
| MEDLINE
| ID: mdl-38879355
ABSTRACT
BACKGROUND:
Radiofrequency ablation (RFA) effectively reduces volume and improves symptoms of benign, non-functioning thyroid nodules (NFTNs). Given RFA's unclear impact on thyroid function, we examined post-RFA trends in thyroid hormones and antibodies.METHODS:
A retrospective cross-sectional analysis was conducted of patients treated at Columbia University with RFA for benign NFTNs between August 2019 and July 2023. Thyroid function tests were recorded pre-RFA and repeated 3, 6, and 12 months post-RFA.RESULTS:
We analyzed 185 patients with 243 benign NFTNs who underwent RFA. Volume reduction ratio increased post-RFA. Mean TSH increased to 2.4 mlU/L (p â= â0.005) at 3 months post-RFA and decreased to 1.8 mlU/L (p â= â0.551) by 12 months post-RFA. Tg and TPO antibody levels peaked at 6 months post-RFA (103.1 IU/mL, p â= â0.868 and 66.6 IU/mL, p â= â0.523, respectively).CONCLUSIONS:
With expected volume reduction post-RFA, we observed transient relative hypothyroidism as well as transient increases in thyroid antibodies, with normalization of these changes within 12 months.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pruebas de Función de la Tiroides
/
Nódulo Tiroideo
/
Ablación por Radiofrecuencia
Límite:
Adult
/
Aged
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Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Am J Surg
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos