Pharmaceuticals and personal care products contamination in the rivers of Chennai city during the COVID-19 pandemic.
Environ Geochem Health
; 46(11): 462, 2024 Oct 01.
Article
en En
| MEDLINE
| ID: mdl-39352591
ABSTRACT
Pharmaceuticals and personal care products (PPCPs) monitoring in surface water is crucial to address the escalating threat of antimicrobial resistance and safeguard public health. This study aimed to investigate the occurrence of 21 different PPCPs, including wastewater chemical markers, antibiotics, and parabens in the surface water of Chennai city using Ultra Performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UPLC-MS/MS) analysis. It is noteworthy that chemical markers viz., carbamazepine (CBZ) and caffeine (CAF) were detected in all the sites and contributed to more than 95% of the total PPCPs load indicating a significant intrusion of wastewater. Among the antibiotics, fluoroquinolones were dominant in this study. Interestingly, a significant and strong correlation was seen between fluoroquinolones, CBZ and CAF (R2 = 0.880-0.928, p < 0.05), suggesting similarities in their sources. More than 50% of the sites exhibited a risk for antimicrobial resistance (RQAMR) with RQAMR > 1 for ciprofloxacin, indicating a significant public health concern. The ecotoxicological risk assessment of PPCPs showed no risk to any organisms, except for triclosan, which posed a risk to fish and daphnids at one site near an open drain in Buckingham canal.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Contaminantes Químicos del Agua
/
Monitoreo del Ambiente
/
Cosméticos
/
Ríos
/
COVID-19
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Environ Geochem Health
Asunto de la revista:
QUIMICA
/
SAUDE AMBIENTAL
Año:
2024
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
Países Bajos