Protective effect of ternatin, a flavonoid isolated from Egletes viscosa less., in experimental liver injury.
Pharmacology
; 48(6): 392-7, 1994 Jun.
Article
en En
| MEDLINE
| ID: mdl-7914024
The effect of ternatin, a tetramethoxyflavone from Egletes viscosa Less., on liver injury induced by carbon tetrachloride (CCl4) was investigated in rats. Twenty-four hours following CCl4 insult (2.5 ml/kg s.c.), changes in the serum enzymes, alanine aminotransferase, aspartate aminotransferase and gamma-glutamyltransferase, as well as liver cell histology were used as indices of hepatic dysfunction. The results show that ternatin (30 mg/kg i.p. daily for 5 consecutive days) causes marked inhibition of CCl4-induced serum enzymes and morbid histologic changes. The observation suggests that ternatin possesses antihepatotoxic activity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plantas Medicinales
/
Flavonoides
/
Hígado
Límite:
Animals
Idioma:
En
Revista:
Pharmacology
Año:
1994
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Suiza