[Meiotic crossing over--not the only source of recombinants in man]. / Meioticheskii krossingover--ne edinstvennyi istochnik rekombinantov u cheloveka.
Genetika
; 29(12): 2000-10, 1993 Dec.
Article
en Ru
| MEDLINE
| ID: mdl-8119579
On the basis of chiasma distributions along bivalents in human male meiosis, genetic lengths were counted for several chromosomal segments. These estimates appeared to be lower than the corresponding genetic lengths produced in the recombination analysis. When al so cytological distances and number of markers used in multilocus mapping were taken into account, the regression estimates of genetic lengths were shown to satisfactorily fit the observed values. This indicates that mitotic crossingover, genetic conversion, mutation and errors in allel's identification in addition to meiotic crossingover, appear to contribute to the observed genetic maps. It is suggested that these namely events, rather than the typing errors suggested by Morton (1991), seem observed over those predicted on the basis of chiasma counts.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Recombinación Genética
/
Intercambio Genético
/
Meiosis
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
/
Male
Idioma:
Ru
Revista:
Genetika
Año:
1993
Tipo del documento:
Article
Pais de publicación:
Rusia