Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.
Nature
; 382(6592): 595-601, 1996 Aug 15.
Article
en En
| MEDLINE
| ID: mdl-8757128
ABSTRACT
An abundant cDNA enriched in Spemann's organizer, cerberus, was isolated by differential screening. It encodes a secreted protein that is expressed in the anterior endomesoderm. Microinjection of cerberus mRNA into Xenopus embryos induces ectopic heads, and duplicated hearts and livers. The results suggest a role for a molecule expressed in the anterior endoderm in the induction of head structures in the vertebrate embryo.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas
/
Inducción Embrionaria
/
Gástrula
/
Cabeza
Límite:
Animals
Idioma:
En
Revista:
Nature
Año:
1996
Tipo del documento:
Article
País de afiliación:
Estados Unidos