mle-1, a mariner-like transposable element in the nematode Trichostrongylus colubriformis.
Gene
; 188(2): 235-7, 1997 Apr 01.
Article
en En
| MEDLINE
| ID: mdl-9133597
ABSTRACT
A mariner-like element termed mle-1 was discovered in the parasitic nematode Trichostrongylus colubriformis. The mle-1 has features which support its assignment as a mariner-like transposable element. Cloned mle-1 was derived from an intron of the tar-1 gene. It comprises 893 bp, includes two 27 bp flanking perfect inverted repeats and is present at approximately 50 copies in the genome. The element contains a coding region which displays homology to transposases, with the greatest amino acid similarity to a Caenorhabditis elegans mariner-like transposase. The coding region contains two 12 bp repeats; these repeats flank an 11 bp segment which accounts for a frameshift in this region. As a candidate transposon, mle-1 provides potential for genetic manipulation of this and related organisms.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trichostrongylus
/
Elementos Transponibles de ADN
/
ADN de Helmintos
Límite:
Animals
Idioma:
En
Revista:
Gene
Año:
1997
Tipo del documento:
Article
País de afiliación:
Australia