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One year of SARS-CoV-2: Genomic characterization of COVID-19 outbreak in Qatar
Fatiha M. Benslimane; Hebah A. AlKhatib; Ola Al-Jamal; Dana Albatesh; Sonia Boughattas; Ayeda A. Ahmed; Meryem Bensaad; Shameem Younuskunju; Yasmin A. Mohamoud; Mashael Al Badr; Abdalla A. Mohamed; Reham A. El Kahlout; Tasneem Al Hamad; Dina Elgakhlab; Fatima H. Al-Kuwari; Chadi Saad; Andrew Jeremijenko; Abdullatif Al-Khal; Muna A. Al-Maslamani; Roberto Bertollini; Einas A. Al-Kuwari; Hamad E. Al-Romaihi; Salih Al-Marri; Mohammed Al-Thani; Radja M. Badji; Hamdi Mbarek; Yasser Al-Sarraj; Joel A Malek; Said I. Ismail; Laith J Abu-Raddad; Peter Coyle; Asmaa A. Althani; HADI M. YASSINE.
Afiliación
  • Fatiha M. Benslimane; Qatar University
  • Hebah A. AlKhatib; Qatar University
  • Ola Al-Jamal; Qatar University
  • Dana Albatesh; Qatar University
  • Sonia Boughattas; Qatar University
  • Ayeda A. Ahmed; Weill Cornell Medicine-Qatar
  • Meryem Bensaad; Weill Cornell Medicine-Qatar
  • Shameem Younuskunju; Weill Cornell Medicine-Qatar
  • Yasmin A. Mohamoud; Weill Cornell Medicine-Qatar
  • Mashael Al Badr; Ministry of Public Health
  • Abdalla A. Mohamed; Ministry of Public Health
  • Reham A. El Kahlout; Hamad Medical Corporation
  • Tasneem Al Hamad; Qatar Biobank
  • Dina Elgakhlab; Qatar Biobank
  • Fatima H. Al-Kuwari; Qatar Genome Program
  • Chadi Saad; Qatar Genome Project
  • Andrew Jeremijenko; Hamad Medical Corporation
  • Abdullatif Al-Khal; Hamad Medical Corporation
  • Muna A. Al-Maslamani; Hamad Medical Corporation
  • Roberto Bertollini; Ministry of Public Health
  • Einas A. Al-Kuwari; Hamad Medical Corporation
  • Hamad E. Al-Romaihi; Ministry of Public Health
  • Salih Al-Marri; Ministry of Public Health
  • Mohammed Al-Thani; Ministry of Public Health
  • Radja M. Badji; Qatar Genome Project
  • Hamdi Mbarek; Qatar Genome Project
  • Yasser Al-Sarraj; Qatar Genome Project
  • Joel A Malek; Weill Cornell Medicine in Qatar
  • Said I. Ismail; Qatar Genome Project
  • Laith J Abu-Raddad; Weill Cornell Medicine-Qatar
  • Peter Coyle; Hamad Medical Corporation
  • Asmaa A. Althani; Qatar University
  • HADI M. YASSINE; Qatar University
Preprint en En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21257433
Artículo de revista
Un artículo publicado en revista científica está disponible y probablemente es basado en este preprint, por medio del reconocimiento de similitud realizado por una máquina. La confirmación humana aún está pendiente.
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ABSTRACT
The state of Qatar has emerged as a major transit hub connecting all parts of the globe, making it as a hotspot for infectious disease introduction and providing an ideal setting to monitor the emergence and spread of variants. In this study, we report on 2634 SARS-CoV-2 whole-genome sequences from infected patients in Qatar between March-2020 and March-2021, representing 1.5% of all positive cases in this period. Despite the restrictions on international travel, the viruses sampled from the populace of Qatar mirrored nearly the entire global populations genomic diversity with nine predominant viral lineages that were sustained by local transmission chains and the emergence of mutations that are likely to have originated in Qatar. We reported an increased number in the mutations and deletions in B.1.1.7 and B.1.351 lineages in a short period. This raises the imperative need to continue the ongoing genomic surveillance that has been an integral part of the national response to monitor SARS-CoV-2 profile and re-emergence in Qatar.
Licencia
cc_by_nc_nd
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Idioma: En Año: 2021 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Idioma: En Año: 2021 Tipo del documento: Preprint