Your browser doesn't support javascript.
loading
Multiplexed Detection of COVID-19 with Single-Molecule Technology
Noa Furth; Shay Shilo; Niv Cohen; Nir Erez; Vadim Fedyuk; Alexander M. Schrager; Adina Weinberger; Amiel A. Dror; Asaf Zigron; Mona Shehadeh; Eyal Sela; Samer Srouji; Sharon Amit; Itzchak Levy; Eran Segal; Rony Dahan; Dan Jones; Danny Doueck; Efrat Shema.
Afiliación
  • Noa Furth; Weizmann Institute of Science
  • Shay Shilo; Weizmann Institute of Science
  • Niv Cohen; Weizmann Institute of Science
  • Nir Erez; Weizmann Institute of Science
  • Vadim Fedyuk; Weizmann Institute of Science
  • Alexander M. Schrager; National Institutes of Health
  • Adina Weinberger; Weizmann Institute of Science
  • Amiel A. Dror; Galilee Medical Center
  • Asaf Zigron; Galilee Medical Center
  • Mona Shehadeh; Galilee Medical Center
  • Eyal Sela; Galilee Medical Center
  • Samer Srouji; Galilee Medical Center
  • Sharon Amit; Sheba medical center
  • Itzchak Levy; Sheba medical center
  • Eran Segal; Weizmann Institute
  • Rony Dahan; Weizmann Institute of Science
  • Dan Jones; SeqLL
  • Danny Doueck; NIH Vaccine Research Center
  • Efrat Shema; Weizmann Institute of Science
Preprint en En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21257501
ABSTRACT
The COVID-19 pandemic raises the need for diverse diagnostic approaches to rapidly detect different stages of viral infection. The flexible and quantitative nature of single-molecule imaging technology renders it optimal for development of new diagnostic tools. Here we present a proof-of-concept for a single-molecule based, enzyme-free assay for detection of SARS-CoV-2. The unified platform we developed allows direct detection of the viral genetic material from patients samples, as well as their immune response consisting of IgG and IgM antibodies. Thus, it establishes a platform for diagnostics of COVID-19, which could also be adjusted to diagnose additional pathogens.
Licencia
cc_by_nc_nd
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Idioma: En Año: 2021 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Idioma: En Año: 2021 Tipo del documento: Preprint