Your browser doesn't support javascript.
loading
SARS-CoV-2 neutralization after mRNA vaccination and variant breakthrough infection
Christian Gaebler; Justin DaSilva; Eva Bednarski; Frauke Muecksch; Fabian Schmidt; Yiska Weisblum; Katrina Millard; Martina Turroja; Alice Cho; Zijun Wang; Marina Caskey; Michel C. Nussenzweig; Paul Bieniasz; Theodora Hatziioannou.
Afiliación
  • Christian Gaebler; The Rockefeller University
  • Justin DaSilva; The Rockefeller University, New York
  • Eva Bednarski; The Rockefeller University, New York
  • Frauke Muecksch; The Rockefeller University, New York, NY
  • Fabian Schmidt; The Rockefeller University, New York
  • Yiska Weisblum; The Rockefeller University, New York
  • Katrina Millard; The Rockefeller University, New York
  • Martina Turroja; The Rockefeller University, New York
  • Alice Cho; The Rockefeller University, New York
  • Zijun Wang; The Rockefeller University, New York
  • Marina Caskey; The Rockefeller University
  • Michel C. Nussenzweig; The Rockefeller University, New York
  • Paul Bieniasz; Rockefeller University
  • Theodora Hatziioannou; The Rockefeller University, New York
Preprint en Inglés | medRxiv | ID: ppmedrxiv-22270692
ABSTRACT
Vaccination and infection by viral variants are shaping population immunity to SARS-CoV-21 and breakthrough infections of vaccinated or previously infected individuals have become common as variants evade preexisting immunity. Omicron (B.1.1.529) is highly resistant to plasma neutralizing antibodies elicited by infection with prior variants and the 2-dose mRNA vaccination regimens. However, vaccination after infection or a third mRNA vaccine dose elicit high levels of neutralizing antibodies that can also neutralize omicron to a degree2-4. We compared neutralizing antibody titers in 54 individuals that had received 2 or 3 doses of mRNA vaccines and had experienced breakthrough infection with SARS-CoV-2 variants.
Licencia
cc_by_nc
Texto completo: Disponible Colección: Preprints Base de datos: medRxiv Idioma: Inglés Año: 2022 Tipo del documento: Preprint
Texto completo: Disponible Colección: Preprints Base de datos: medRxiv Idioma: Inglés Año: 2022 Tipo del documento: Preprint
...