A new antimicrobial isobenzoisofuran compound from Cassia pumila / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 896-898, 2020.
Article
en Zh
| WPRIM
| ID: wpr-1008516
Biblioteca responsable:
WPRO
ABSTRACT
A new isobenzoisofuran(1) has been isolated from the whole plant of Cassia pumila using various chromatographic techniques, including silica gel, Sephadex, MCI-gel resin, and RP-HPLC, and its structure was determined as 9-(2-hydroxyethyl)-2,2-dimethyl-2H-furo[3,4-g]chromen-6(8H)-one. This compound was also evaluated for its antibacterial activity. The results showed that it had prominent antibacterial activity with MIC_(90) value of(45.2±4.2) μg·mL~(-1) for methicillin resistant Staphylococcus aureus(MRSA) strain. This value was closed to that of levofloxacin [with MIC_(90) value(48.5±4.3) μg·mL~(-1)].
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Plantas Medicinales
/
Benzofuranos
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Cassia
/
Pruebas de Sensibilidad Microbiana
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Staphylococcus aureus Resistente a Meticilina
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Levofloxacino
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Fitoquímicos
/
Antibacterianos
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2020
Tipo del documento:
Article