Metabonomics in study of Parkinson's disease biomarkers / 中华神经医学杂志

ABSTRACT

Parkinson's disease (PD) is a common neurological degenerative diseases.Neuron degeneration process is irreversible;therefore,the correct diagnosis is critical and reliable biomarkers are urgently needed.With the development of molecular biology,some nonspecific biomarker detection methods,such as metabolomics,have been used in the study ofPD.Metabonomics provides a technology and a new technical platform for testing comprehensive metabolites of PD.Metabonomics is very important for biomarker screening in PD.In this paper,the concept,research methods and research progress of metabonomics in PD are reviewed.