Frontoparietal Cortical Thinning in Respiratory-Type Panic Disorder: A Preliminary Report
Psychiatry Investigation
; : 146-151, 2016.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-108173
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE:
Many evidences raise the possibility that the panic disorder (PD) patients with respiratory subtype (RS) may have characteristic structural abnormalities. We aimed to explore the structural differences between PD patients with and without the respiratory symptoms.METHODS:
Patients with PD were recruited from the Department of Psychiatry at Korea University Anam Hospital. Respiratory subtype (RS) was diagnosed when at least 4 out of 5 of the following respiratory symptoms were present during the panic attack fear of dying, chest pain/discomfort, shortness of breath, paresthesias, and a choking sensation. We acquired high-resolution MRI scans and used FreeSurfer to obtain a measure of cortical thickness for each patient.RESULTS:
Cluster based analysis revealed significantly decreased cortical thickness in the left hemisphere in the caudal-middle-frontal, superior frontal, and posterior parietal areas in the RS group. No significant difference was observed in any of the limbic areas.CONCLUSION:
Respiratory symptoms of panic disorder were associated with a reduction in cortical thickness in the left frontal and parietal areas. This finding leads to the assumption that the frontoparietal network is the crucial component in a larger cortical network underlying the perception of dyspnea in RS.
Texto completo:
Disponible
Contexto en salud:
ODS3 - Meta 3.4 Reducir las muertes prematuras por enfermedades no transmisibles
Problema de salud:
Salud Mental y Trastornos del Comportamiento
/
Otras Enfermedades Respiratorias
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Pánico
/
Parestesia
/
Sensación
/
Tórax
/
Imagen por Resonancia Magnética
/
Trastorno de Pánico
/
Obstrucción de las Vías Aéreas
/
Disnea
/
Rabeprazol
/
Corea (Geográfico)
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Psychiatry Investigation
Año:
2016
Tipo del documento:
Artículo