The Health Effects of Mercury on the Cardiac Autonomic Activity According to the Heart Rate Variability / 대한산업의학회지
Korean Journal of Occupational and Environmental Medicine
; : 302-313, 2008.
Artículo
en Coreano
| WPRIM (Pacífico Occidental)
| ID: wpr-115625
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVES:
The effect of mercury on the cardiovascular system has recently been reported on, but the mechanisms as well as its nature of this effect still need to be confirmed. In this study, the mercury in the hair of a community population was analyzed in relation to the cardiac autonomic activity.METHODS:
A hair sample was obtained from the occiput area and the mercury in the hair was analyzed by using a Direct Mercury Analyzer. We measured the cardiovascular risk factors, including total cholesterol, triglyceride, blood pressure, and the body mass index (BMI). Heart rate variability was assessed for 5 minutes, in the time and frequency domain, by using SA-3000P from the Medi-core(R). company. The association between the mercury in the hair and heart rate variability was assessed after controlling for the other cardiovascular risk factors.RESULTS:
The mean age of the 671 total subjects was 36 years. The geometric mean of the hair mercury was 0.90 ppm. The hair mercury level was elevated in males, adults, smokers and drinkers. Hair mercury and age, the systolic and diastolic blood pressure, total cholesterol, triglyceride, LDL cholesterol and BMI were all positively correlated. However, hair mercury and heart rate, HDL cholesterol, standard deviation of the NN intervals (SDNN), total power (TP), low-frequency (LF), high- frequency (HF) were negatively correlated. In the higher mercury group, heart rate, SDNN, LF and HF indices were significantly lower compared with those of the lower mercury group. Heart rate was decreased 2.6 beats/min, Ln (HF) was decreased 0.131 msec2 and HF norm was decreased 2.550 with a 1 ppm increase of Ln (Hg), according to multiple linear regression analysis after controlling for age, gender and other cardiovascular risk factors.CONCLUSION:
This cross-sectional study showed that mercury may affect the cardiac autonomic activity through parasympathetic dysfunction.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Sistema Nervioso Autónomo
/
Presión Sanguínea
/
Sistema Cardiovascular
/
Índice de Masa Corporal
/
Modelos Lineales
/
Colesterol
/
Estudios Transversales
/
Factores de Riesgo
/
Cabello
/
Corazón
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Occupational and Environmental Medicine
Año:
2008
Tipo del documento:
Artículo