Comparison of Clinical Outcomes between Pylorus Preserving Pancreaticoduodenectomy and Pancreaticoduodenectomy / 한국간담췌외과학회지
Korean Journal of Hepato-Biliary-Pancreatic Surgery
; : 214-219, 2003.
Article
en Ko
| WPRIM
| ID: wpr-163926
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: A pancreaticoduodenectomy (PD) and pylorus-preserving pancreaticoduodenectomy (PPPD) are the two methods commonly used to treat periampullary neoplasms. This study was designed to compare these two methods in terms of the post-operative complications, the recurrence rate, and the post-operative weight change. METHODS: The medical records of 110 patients who underwent PD or PPPD from February 1986 through to June 2002 were retrospectively reviewed. The PD was performed on 54 patients and PPPD was performed on 56 patients, respectively. The mean follow-up periods were 25.33 months in the PD group and 25.39 months in the PPPD group, respectively. RESULTS: Diabetes mellitus occurred in 9 patients (16.7%) in the PD group and 8 patients (14.3%) in the PPPD group, and gastric emptying was delayed in 14 (25.9%) and 15 (26.8%) patients of each group after surgery. Procedure related deaths occurred in 2 (3.7%) and 4 (7.1%) patients from each group. There were no statistically significant differences in the post-operative complications between the two groups. The disease recurrence rate was significantly lower in the PPPD group than in the PD group (60.5% vs. 22.9%, p=0.001). Post-operative weight loss just after surgery at 3 months and 6 months after surgery was 3.56 kg, 3.68 kg, and 3.97 kg in the PD group and 2.78 kg, 1.77 kg, and 1.8 kg in the PPPD group, respectively, without showing a statistically significant difference. CONCLUSION: The clinical outcomes of the PPPD was not different from those of the PD in terms of the post-operative complications and weight loss. The disease recurrence rate was lower in the PPPD group. These results suggest that PPPD could be the treatment choice periampullary neoplasms.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Píloro
/
Recurrencia
/
Pérdida de Peso
/
Registros Médicos
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Pancreaticoduodenectomía
/
Diabetes Mellitus
/
Vaciamiento Gástrico
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Hepato-Biliary-Pancreatic Surgery
Año:
2003
Tipo del documento:
Article