Esthesioneuroblastoma in a boy with 47, XYY karyotype / 소아과
Korean Journal of Pediatrics
; : S92-S95, 2016.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-201852
Biblioteca responsable:
WPRO
ABSTRACT
Neuroblastomas are sometimes associated with abnormal constitutional karyotypes, but the XYY karyotype has been rarely described in neuroblastomas. Here, we report a case of an esthesioneuroblastoma in a boy with a 47, XYY karyotype. A 6-year-old boy was admitted to our hospital because of nasal obstruction and palpable cervical lymph node, which he first noticed several days previously. A polypoid mass in the right nasal cavity was detected through sinuscopy. Biopsy of the right nasal polyp was performed. Based on the result, the patient was diagnosed with a high-grade esthesioneuroblastoma. Nuclear imaging revealed increased uptake in both the right posterior nasal cavity and the right cervical IB-II space, suggesting metastatic lymph nodes. Cytogenetic analysis revealed a 47, XYY karyotype. Twelve courses of concurrent chemotherapy were administered. Three years after the completion of chemotherapy, the patient had had no disease recurrence. He manifested behavioral violence and temper tantrums, so we started methylphenidate for correction of the behavior.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Recurrencia
/
Violencia
/
Cariotipo XYY
/
Biopsia
/
Obstrucción Nasal
/
Pólipos Nasales
/
Aberraciones Cromosómicas
/
Estesioneuroblastoma Olfatorio
/
Análisis Citogenético
/
Quimioterapia
Aspecto:
Determinantes sociales de la salud
Límite:
Niño
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Korean Journal of Pediatrics
Año:
2016
Tipo del documento:
Artículo