Serotonin Syndrome After an Overdose of Dextromethorphan and Chlorpeniramine: Two Case Reports
Journal of The Korean Society of Clinical Toxicology
; : 19-22, 2013.
Article
en Ko
| WPRIM
| ID: wpr-212416
Biblioteca responsable:
WPRO
ABSTRACT
Dextromethorphan and chlorpeniramine are common ingredients of over-the-counter (OTC) cough pills. They are known to be safe when used alone, however, combination with other serotonergic drugs or use of an overdose can cause serotonergic toxicity. We report on a 43-year-old male and a 57-year-old female who ingested an overdose of antitussive drugs containing dextromethorphan and chlorpeniramine. They commonly presented with altered mentality and hyperreflexia on both upper and lower extremities. After conservative therapies, they were discharged with alert mentality. These cases are meaningful in that there are few cases of serotonin syndrome with an overdose of a combination of dextromethorphan and chlorpeniramine. Careful use with medication counseling for OTC cough pills is needed in order to prevent overdose of these ingredients.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Antitusígenos
/
Serotonina
/
Reflejo Anormal
/
Serotoninérgicos
/
Síndrome de la Serotonina
/
Tos
/
Consejo
/
Extremidad Inferior
/
Dextrometorfano
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Ko
Revista:
Journal of The Korean Society of Clinical Toxicology
Año:
2013
Tipo del documento:
Article