A case of oxaliplatin-induced immune-mediated thrombocytopenia
Blood Research
; : 61-64, 2014.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-228926
Biblioteca responsable:
WPRO
ABSTRACT
Oxaliplatin is a platinum compound used in patients with gastrointestinal malignancies. It is known to evoke a drug-induced immune-mediated thrombocytopenia, which has not been reported in Korea. We describe a 53-year-old man who developed oxaliplatin-induced immune-mediated thrombocytopenia during chemotherapy for colon cancer. Oxaliplatin-dependent IgG platelet antibodies were detected in his serum on flow cytometry. He was treated with immunoglobulin and corticosteroids without any complications. Physicians should consider oxaliplatin-induced immune-mediated thrombocytopenia, when a sudden, isolated thrombocytopenia develops during chemotherapy with oxaliplatin.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Platino (Metal)
/
Trombocitopenia
/
Plaquetas
/
Inmunoglobulina G
/
Inmunoglobulinas
/
Corticoesteroides
/
Neoplasias del Colon
/
Quimioterapia
/
Citometría de Flujo
/
Corea (Geográfico)
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Blood Research
Año:
2014
Tipo del documento:
Artículo