Correlation between lacunar cerebral infarction and serum uric acid level in elderly male hypertension patients / 中国应用生理学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the correlation between lacunar cerebral infarction and level of serum uric acid in elderly male hypertension patients.</p><p><b>METHODS</b>Ninety-eight elderly male hypertension patients were enrolled in this study. They all underwent cerebral magnetic resonance imaging (MRI) scan, and their clinical and laboratory data were collected. The patients were divided into the 1st group (n = 32), the 2nd group (n = 32) and the 3rd group (n = 34) according to the level of serum uric acid.</p><p><b>RESULTS</b>The numbers of lacuner infarction, serum creatinine, urea and high density lipoprotein(HDL) were significantly diferrent from the other groups. The numbers of lacuner infarction were positively related with serum uric acid and urea. Multiple variant analysis showed that serum uric acid was the independent factor of the numbers of lacuner infarction.</p><p><b>CONCLUSION</b>The elevated level of serum uric acid may contribute to the risk factors of lacuner infarction.</p>