Short-term medication of L-carnitine before intracytoplasmic sperm injection for infertile men with oligoasthenozoospermia / 中华男科学杂志
National Journal of Andrology
; (12): 253-256, 2012.
Article
en Zh
| WPRIM
| ID: wpr-238987
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the pregnancy promoting effect of L-carnitine combined with intracytoplasmic sperm injection (ICSI) in treating male infertility with oligoasthenozoospermia.</p><p><b>METHODS</b>We assigned 129 patients with oligoasthenozoospermia to receive 2 weeks of oral L-carnitine followed by ICSI (medication group, n = 42) and ICSI alone (control group, n = 87). We compared the sperm concentration and motility, the percentage of grade a + b sperm, and sperm deformity before and after L-carnitine medication, as well as the rates of fertilization, cleavage, available embryo and clinical pregnancy between the two groups.</p><p><b>RESULTS</b>The percentage of grade a + b sperm was significantly increased after L-carnitine medication as compared with the baseline ([13.5 +/- 10.7] % vs [9.6 +/- 7.2] %, P<0.05), and so was the rate of available embryo in the medication group after ICSI in comparison with that of the control group (77.50% vs 69.04%, P<0.05).</p><p><b>CONCLUSION</b>Short-term medication of L-carnitine can improve sperm quality and raise the success rate of ICSI.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Oligospermia
/
Terapéutica
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Resultado del Embarazo
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Carnitina
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Inyecciones de Esperma Intracitoplasmáticas
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Usos Terapéuticos
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Astenozoospermia
/
Infertilidad Masculina
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Métodos
Límite:
Adult
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Female
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Humans
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Male
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Pregnancy
Idioma:
Zh
Revista:
National Journal of Andrology
Año:
2012
Tipo del documento:
Article