Studies on the safety and immunogenicity of lyophilized live attenuated measles-mumps-rubella combined vaccine / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 435-437, 2002.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-244250
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the safety and immunogenicity of the measles-mumps-rubella combined vaccine (MMR) produced by Beijing Biological Product Institute.</p><p><b>METHODS</b>Children aged 10-12 years, 2-2.5 years and 8-12 months were selected to be vaccinated with Beijing MMR vaccine (test vaccine). Other groups of children with similar nature were vaccinated with measles vaccine, mumps vaccine and rubella vaccine while using imported MMR vaccine (control vaccine) as controls.</p><p><b>RESULTS</b>The safety of the Beijing MMR vaccine was confirmed after vaccinating 32 children above 2 years old. Among 104 children of 8-12 months were vaccinated with Beijing MMR vaccine, only 6.7% of the children had transient fever and 1.9% had signs of rashes but with no other signs observed. The positive seroconversion rates of measles, rubella and mumps anti-HI were 100%, 100% and 85.7% respectively. GMT also showed high lever.</p><p><b>CONCLUSION</b>The MMR vaccine (Beijing) had good safety and immunogenicity which might be used to be the bases enhance immunization of measles.</p>
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Sangre
/
Pruebas de Inhibición de Hemaglutinación
/
Vacunas Atenuadas
/
Vacuna contra el Sarampión-Parotiditis-Rubéola
/
Alergia e Inmunología
/
Liofilización
/
Anticuerpos Antivirales
Límite:
Niño
/
Niño, preescolar
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Epidemiology
Año:
2002
Tipo del documento:
Artículo