Distribution of hepatitis B virus genotype B subgenotype in China / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the distribution of hepatitis B virus (HBV) genotype B subgenotype in China.</p><p><b>METHODS</b>A cohort of 511 patients with chronic HBV genotype B infection, collected from 7 centers across China, were analyzed by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) or nucleotide sequencing.</p><p><b>RESULTS</b>For the 511 patients, only subgenotype Ba was identified and subgenotype Bj was not found.</p><p><b>CONCLUSION</b>In China, subgenotype Ba was the most prevalent HBV strains, while subgenotype Bj was very rarely found.</p>