Research advances in the application of methylprednisolone in the treatment of acute spinal cord injury / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 680-685, 2014.
Artículo
en Inglés
| WPRIM (Pacífico Occidental)
| ID: wpr-257694
Biblioteca responsable:
WPRO
ABSTRACT
Acute spinal cord injury(ASCI),mainly caused by traffic accidents and fall injuries,is a catastrophic event that can profoundly affect the trajectory of a patient's life. Debate continues over the medical management of ASCI,in particular the usefulness,dosage,and potential risks of methylprednisolone(MP). Although the results of American National Acute Spinal Cord Injury Study 2 and 3 trials led to the wide adoption of a high-dose MP regimen for ASCI patients,the reliabilities of their study methods and data were still questionable. Based on the currently available literature,we conclude that high-dose MP is no longer a recommended therapy for ASCI;however,due to the lack of effective treatment,it remains a useful option for this condition.
Texto completo:
Disponible
Base de datos:
WPRIM (Pacífico Occidental)
Asunto principal:
Traumatismos de la Médula Espinal
/
Metilprednisolona
/
Ensayos Clínicos como Asunto
/
Resultado del Tratamiento
/
Fármacos Neuroprotectores
/
Usos Terapéuticos
/
Quimioterapia
Límite:
Humanos
Idioma:
Inglés
Revista:
Acta Academiae Medicinae Sinicae
Año:
2014
Tipo del documento:
Artículo