Burden and related factors among care-takers of patients with Parkinson's disease / 中华流行病学杂志

ABSTRACT

Objective To assess the impact on caretaker who looked after patients with Parkinson's disease(PD) and to identify the main factors related to their burden.Methods 115 consecutive pairs of PD patients and their caretakers were included.Caregiver Burden Inventory (CBI) was used to assess the burden of PD on the caretakers.Patients were evaluated by neurologists using the United Parkinson's Disease Rating Scale(UPDRS),the Hoehn and Yahr Scale(H-Y Scale),the Activity of Daily Liring Scale(ADL),the Parkinson's Disease Quesnonnaire(PDQ-39),the Hamilton Depression Rating Scale(HAMD),the Hamilton Anxiety Rating Scale(HAMA),the Montreal Cognitive Assessment(MoCA)and the Mini-mental State Examination(MMSE).Multiple linear stepwise regression models were fired to ascertain the factors linked to the CBI.Results Based on multiple linear stepwise regression analysis,ADL(β=-0.813,t=-6.265,P=0.000)and PDQ-39(β=0.285,t=4.256,P=0.000)of patients and the age ofcaretakers(β=0.327,t=3.107,P=0.002)proved to be the main predictors of CBI.Conclusion Many factors might comprehensively affct the burden of PD on caretakers of the patients.Attention needs to be given to the early identification of factors that generating stress on 1iveretakers in order to improve their quality of life.