Symptom-based traditional Chinese medicine slices relationship network and its network pharmacology study / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2916-2919, 2011.
Article
en Zh
| WPRIM
| ID: wpr-293152
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To discover and interpret the correlations between traditional Chinese medicine (TCM) slices and their properties such as function, symptom and channel tropism by constructing the relationship network using network pharmacology approaches.</p><p><b>METHOD</b>TCM slices related information was extracted from Chinese Pharmacopeia (2010 edition, volume I) by text mining, and was used to construct the TCM slices-symptom relationship network. The corresponding network analysis was also performed.</p><p><b>RESULT</b>Three thousands and sixteen pair of TCM slice-symptom correlation associated with 646 TCM slices was discovered, and the constructed network unfolded the complex relationships between TCM slices. Further network analysis results indicated that the un-annotated function and channel tropism of TCM slice can be revealed by proposed symptom-based network.</p><p><b>CONCLUSION</b>Network pharmacology approaches can be applied in TCM research to discover and interpret the relationships between TCM slices and their properties.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Farmacología
/
Medicamentos Herbarios Chinos
/
Interacciones Farmacológicas
/
Quimioterapia
/
Medicina Tradicional China
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2011
Tipo del documento:
Article