Simultaneous determination of six ingredients in Huoxiang Zhengqi oral liquid by UPLC / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2314-2317, 2013.
Article
en Zh
| WPRIM
| ID: wpr-315035
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To develop a UPLC method for the simultaneous determination of liquiritin, narirutin, hesperidin, ammonium glycyrrhetate, honokiol and magnolol in Huoxiang Zhengqi oral liquid.</p><p><b>METHOD</b>A Zorbax Eclipse C18 column was used with the mobile phase of acetonitrile and 0. 05% phosphate acid by gradient elution at the detection wavelength of 220 nm. The flow rate was 0.42 mL x min(-1) and the column temperature was 30 degrees C.</p><p><b>RESULT</b>The calibration curves were linear in the ranges of 0.001 7-0.034, 0.003 4-0.068, 0.006 4-0.128, 0.012 8-0.256, 0.003 2-0.064, 0.006 4-0.128 microg, respectively. The average recoveries were 103.3%, 98.39%, 98.29%, 102.1%, 98.45%, 102.2% with RSDs of 2.1%,1.0%, 0.50%, 2.3%, 0.9%, 2.0%, respectively.</p><p><b>CONCLUSION</b>The UPLC method was simple, rapid and accurate, it could be used for quality control of Huoxiang Zhengqi oral liquid.</p>
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Base de datos:
WPRIM
Asunto principal:
Compuestos de Bifenilo
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Medicamentos Herbarios Chinos
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Química
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Administración Oral
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Cromatografía Líquida de Alta Presión
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Lignanos
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Soluciones Farmacéuticas
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Flavanonas
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Disacáridos
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Glucósidos
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2013
Tipo del documento:
Article